Description

Depalgos 20 mg + 325 mg

Depalgos 20 mg + 325 mg is used for the Treatment of moderate to severe degenerative pain in the course of musculoskeletal disorders not controlled by (NSAID) / paracetamol used alone. – Treatment of moderate to severe cancer pain.
DEPALGOS 5 mg + 325 mg film-coated tablets One tablet contains: Active ingredients: Oxycodone hydrochloride 5 mg Paracetamol 325 mg For the complete list of excipients, see section 6.1. DEPALGOS 10 mg + 325 mg film-coated tablets One tablet contains Active ingredients: Oxycodone hydrochloride 10 mg Paracetamol 325 mg For the complete list of excipients. DEPALGOS 20 mg + 325 mg film-coated tablets one tablet contains Active ingredients: Oxycodone hydrochloride 20 mg Paracetamol 325 mg For the complete list of excipients,

Initial dosage

• Patients receiving opioids for the first time or with pain not controlled by other weak opioids:The daily dose is represented by one tablet “5 mg + 325 mg” every 6 hours.
• Previously treated patients with strong opioids:

The starting daily dose should be determined as a function of the previously taken daily opioid dose. When calculating the initial daily dose, it should be considered that the ratio of equity-analgesia between oral oxycodone and oral morphine is approximately 1 to 2 (i.e. 10 mg of oxycodone corresponds to 20 mg of morphine).

The total dose obtained is divided and administered every 6 hours, using the most appropriate tablet among the available strengths (“5 mg + 325 mg”, “10 mg + 325 mg” and “20 mg + 325 mg”).