Description

Oxydolor 80mg (Oxycodone hydrochloride)

Oxydolor 80mg (Oxycodone hydrochloride) and prolonged-release tablets (Oxydolor) are approved for the treatment of moderate to severe pain including steady pain, e.g., cancer pain, paroxysmal spontaneous pain, and allodynia. This prolonged-release oral formulation of Oxydolor hydrochloride is indicated for the management of moderate to severe pain when a continuous, around-the-clock analgesic is needed for an extended period of time. Oxydolor HYDROCHLORIDE prolonged-release tablet (Oxydolor) is not intended for use as a prn analgesic. Physicians should individualize treatment in every case, initiating therapy at the appropriate point along a progression from non-opioid analgesics, such as non-steroidal anti-inflammatory drugs and acetaminophen to opioids in a plan of pain management such as outlined by the World Health Organization.

Composition of the preparation

The active substance and excipients contained in the core are the same in all Oxydolor doses, while the composition of the shell is different for each dose.

Oxydolor prolonged-release tablets contain 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of oxycodone hydrochloride, respectively.
The excipients in the tablet core are: kollidon SR (polyvinyl acetate, povidone (K=27.0 – 32.4), sodium laurilsulfate, silica), microcrystalline cellulose, colloidal anhydrous silica and magnesium stearate.

5 mg tablet coating: polyvinyl alcohol, talc (E553b), titanium dioxide (E171), macrogol 3350, soya lecithin (E322), iron oxide yellow (E172), iron oxide black (E172), indigo carmine (E132) , lacquer

10 mg tablet coating: polyvinyl alcohol, talc (E 553b), titanium dioxide (E171), macrogol 3350, soya lecithin (E 322).

20 mg tablet coating: polyvinyl alcohol, talc (E553b), titanium dioxide (E171), macrogol 3350, soya lecithin (E322), yellow iron oxide (E172), black iron oxide (E172), red iron oxide (E172). ).

40 mg tablet coating: polyvinyl alcohol, talc (E553b), titanium dioxide (E171), macrogol 3350, soya lecithin (E322), yellow iron oxide (E172), black iron oxide (E172), red iron oxide (E172). ).

80 mg tablet coating: polyvinyl alcohol, talc (E553b), titanium dioxide (E171), macrogol 3350, soya lecithin (E322), iron oxide yellow (E172), iron oxide black (E172), indigo carmine (E132) , lacquer

Oxycolor side effects

Like any drug, Oxydolor can cause side effects. Among the most commonly observed are headaches and dizziness, drowsiness, vomiting, constipation, nausea, and itching. In addition, there have also been cases of eating disorders, ranging from decreased appetite, even to anorexia, behavioral disorders such as confusion, anxiety, depression, nervousness, abnormal thinking processes.

Some patients also complained of tremor, shortness of breath, dry mouth or low blood pressure, weakness or increased sweating. Hypersensitivity, agitation, emotional instability, decreased libido , hallucinations, memory problems, hypertonia, and the syndrome of inappropriate secretion of antidiuretic hormone were also much less common. The use of high doses of opioid-based drugs, especially over a long period of time, may be associated with the risk of addiction.